TMJ Disorder and Propranolol

For those that do not get the Goodfellow Unit Gems, the following may be of interest in their post today

200 patients with TMJ pain randomised to 120mg / day propranolol or placebo

NNT for 50% reduction in pain = 6.1


  1. Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network and Orofacial Pain Special Interest Group. J Oral Facial Pain Headache (2014)  View here
  2. Efficacy and safety of propranolol for treatment of temporomandibular disorder pain: a randomized, placebo-controlled clinical trial Pain (2020)

Jenny Keightley

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